Longevity and other practical benefits of monolithic silica columns in the analysis of samples with complex matrices

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F23%3A10471650" target="_blank" >RIV/00179906:_____/23:10471650 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11160/23:10471650

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=5xL20Xt1NP" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=5xL20Xt1NP</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/jssc.202300448" target="_blank" >10.1002/jssc.202300448</a>

Result language

angličtina

Original language name

Longevity and other practical benefits of monolithic silica columns in the analysis of samples with complex matrices

Original language description

At the turn of the millennium, the monolithic columns invoked new chances in HPLC. Even more than their organic polymer-based siblings, the inorganic silica-based monoliths targeted the territory of classical fully porous particle-packed columns, promising many benefits. Based on the number of published articles, the monoliths attracted academics just in the first few years after their introduction to the market. Lately, as superficially porous particles and sub-2-micron fully porous particles dominated the market, they stayed in the focus of routine laboratories and those who really appreciated the high porosity of the monolithic bed. The monoliths&apos; practical benefits cannot be easily traced in the literature when they gradually lose academics&apos; interest. Nevertheless, after more than 20 years of our experience, we still favor silica monoliths for their low back pressure and longevity when analyzing samples of clinical, pharmaceutical, and environmental origin. At the same time, the high permeability of monoliths enabled the birth of sequential injection chromatography, the medium-pressure separation technique based on the flexible flow manifold. This minireview aims to check, discuss, and summarize the practical aspects of monolithic silica columns in HPLC and medium-pressure sequential injection chromatography (SIC) that may not be visible at first sight but are evident retrospectively.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30104 - Pharmacology and pharmacy

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Separation Science

ISSN

1615-9306

e-ISSN

1615-9314

Volume of the periodical

46

Issue of the periodical within the volume

18

Country of publishing house

DE - GERMANY

Number of pages

7

Pages from-to

e2300448

UT code for WoS article

001049229700001

EID of the result in the Scopus database

2-s2.0-85167981401