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Evaluation of innate lymphoid cells and their subsets in atopic dermatitis patients with and without dupilumab therapy

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F24%3A10473166" target="_blank" >RIV/00179906:_____/24:10473166 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11150/24:10473166

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=TlidJ1va11" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=TlidJ1va11</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1080/09546634.2023.2299721" target="_blank" >10.1080/09546634.2023.2299721</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Evaluation of innate lymphoid cells and their subsets in atopic dermatitis patients with and without dupilumab therapy

  • Original language description

    The aim of the study is to evaluate the count of innate lymphoid cells (ILCs) and their types (ILC -1, ILC-2, ILC-3, ILC-3 NCR+, ILC-3 NCR-) in atopic dermatitis (AD) patients with and without dupilumab therapy and evaluate the relation to the severity of atopic dermatitis. In AD patients without dupilumab therapy, we confirmed the significantly lower count of total ILCs, ILC-2 and ILC-3 NCR-. The relation between the severity of AD and the count of ILC cells and their subsets was not confirmed. Our results suggest that dupilumab affects the count of ILC cells. Dupilumab normalizes the level of ILC cells in peripheral blood (total, ILC- 2 and ILC-3 NCR-).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30216 - Dermatology and venereal diseases

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Dermatological Treatment

  • ISSN

    0954-6634

  • e-ISSN

    1471-1753

  • Volume of the periodical

    35

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    4

  • Pages from-to

    2299721

  • UT code for WoS article

    001136924300001

  • EID of the result in the Scopus database

    2-s2.0-85181518818