The Role of Adjuvant Radiotherapy in the Treatment of Breast Cancer
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F24%3A10481214" target="_blank" >RIV/00179906:_____/24:10481214 - isvavai.cz</a>
Alternative codes found
RIV/60162694:G44__/25:00563222 RIV/00216208:11150/24:10481214 RIV/61989592:15110/24:73629014 RIV/00216275:25520/24:39922641 RIV/00098892:_____/24:10158613
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=KAMMwuOJXB" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=KAMMwuOJXB</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/curroncol31030090" target="_blank" >10.3390/curroncol31030090</a>
Alternative languages
Result language
angličtina
Original language name
The Role of Adjuvant Radiotherapy in the Treatment of Breast Cancer
Original language description
The role of postmastectomy radiotherapy and regional nodal irradiation after radical mastectomy is defined in high-risk patients with locally advanced tumors, positive margins, and unfavorable biology. The benefit of postmastectomy radiotherapy in intermediate-risk patients (T3N0 tumors) remains a matter of controversy. It has been demonstrated that radiotherapy after breast-conserving surgery lowers the locoregional recurrence rate compared with surgery alone and improves the overall survival rate. In patients with four or more positive lymph nodes or extracapsular extension, regional lymph node irradiation is indicated regardless of the surgery type (breast-conserving surgery or mastectomy). Despite the consensus that patients with more than three positive lymph nodes should be treated with radiotherapy, there is controversy regarding the recommendations for patients with one to three involved lymph nodes. In patients with N0 disease with negative findings on axillary surgery, there is a trend to administer regional lymph node irradiation in patients with a high risk of recurrence. In patients treated with neoadjuvant systemic therapy and mastectomy, adjuvant radiotherapy should be administered in cases of clinical stage III and/or >= ypN1. In patients treated with neoadjuvant systemic therapy and breast-conserving surgery, postoperative radiotherapy is indicated irrespective of pathological response.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30204 - Oncology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Current Oncology
ISSN
1198-0052
e-ISSN
1718-7729
Volume of the periodical
31
Issue of the periodical within the volume
3
Country of publishing house
CA - CANADA
Number of pages
14
Pages from-to
1207-1220
UT code for WoS article
001191531400001
EID of the result in the Scopus database
2-s2.0-85188813171