Gut-brain axis and Alzheimer's disease: Therapeutic interventions and strategies
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F24%3A10481215" target="_blank" >RIV/00179906:_____/24:10481215 - isvavai.cz</a>
Alternative codes found
RIV/62690094:18470/24:50020874
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=GziUgK25V1" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=GziUgK25V1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jff.2023.105915" target="_blank" >10.1016/j.jff.2023.105915</a>
Alternative languages
Result language
angličtina
Original language name
Gut-brain axis and Alzheimer's disease: Therapeutic interventions and strategies
Original language description
The effects of the gut microbiome on the brain and the mechanisms of gut-brain communication have been popular research topics for the past few decades. The term gut-brain axis (GBA) evolved to illustrate how the gut and gut microbiota communicate with the brain. The gut-brain axis is an interplay of the neural, endocrine, immune, and metabolic pathways that help to maintain the brain's homeostasis. Several groups have reported that gut dysbiosis is significantly associated with neuroinflammation, aggregation of amyloid beta, and an increase in oxidative stress during Alzheimer's disease (AD). Understanding the exact mechanism of how the gut microbiome influences brain function may help develop new therapeutic modalities for AD. This review highlights the functioning of the gut microbiome in AD pathogenesis, the potential beneficial effects of probiotic exopolysaccharides as therapeutic molecules, and the potential benefits of probiotic exopolysaccharides (EPS) as a ray of hope in treating AD.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30308 - Nutrition, Dietetics
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Functional Foods
ISSN
1756-4646
e-ISSN
2214-9414
Volume of the periodical
112
Issue of the periodical within the volume
JAN
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
11
Pages from-to
105915
UT code for WoS article
001128425100001
EID of the result in the Scopus database
2-s2.0-85178437767