Sensitization to latex and food allergens in atopic dermatitis patients according to ALEX2 Allergy Xplorer test
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F24%3A10485337" target="_blank" >RIV/00179906:_____/24:10485337 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/24:10485337
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=mljnEN-uNe" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=mljnEN-uNe</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.molimm.2024.09.002" target="_blank" >10.1016/j.molimm.2024.09.002</a>
Alternative languages
Result language
angličtina
Original language name
Sensitization to latex and food allergens in atopic dermatitis patients according to ALEX2 Allergy Xplorer test
Original language description
AAim of our study is to analyse the sensitisation profile to molecular components of latex and of food allergens with the use of ALEX2 Allergy Xplorer test and to compare these results with the anamnestical data after latex exposure and with the anamnestical data after exposure to food allergens in atopic dermatitis patients. Methods: 100 patients were included in the study (49 men and 51 women with the average age 40.6 years). The specific IgE was examined with the use of ALEX2 Allergy Xplorer test. A detailed personal history of allergic reaction to latex and allergic reaction to food allergens was taken in all included patients. Results: The sensitisation to latex was recorded in 17 % of patients, majority of patients have positive results of specific IgE to Hev b 8 without clinical reaction to latex. In 7 % of patients with positive results of specific IgE to Hev b 1, Hev b 3, Hev b 5, Hev b 6.02 and Hev b 11 the contact urticaria or contact dermatitis were recorded. The latex fruit syndrome was recorded in 7 % of patients; in another 10% of patients we recorded no clinical reaction to latex, but the positive results to molecular components of latex and the clinical symptoms after ingestion of different kinds of fruits. Conclusion: The significant relation between the results of specific IgE to molecular components Hev b 3, Hev b 5 and Hev b 6.02 and the clinical reaction to latex was confirmed; these components significantly imply clinical reactivity to latex.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30216 - Dermatology and venereal diseases
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Molecular Immunology
ISSN
0161-5890
e-ISSN
1872-9142
Volume of the periodical
25
Issue of the periodical within the volume
175
Country of publishing house
GB - UNITED KINGDOM
Number of pages
14
Pages from-to
89-102
UT code for WoS article
001325006200001
EID of the result in the Scopus database
2-s2.0-85204764958