Computed tomography-guided percutaneous biopsy in diagnosis of suspected metastatic renal cell carcinoma: which location is the most suitable?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F24%3A10490981" target="_blank" >RIV/00179906:_____/24:10490981 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/24:10490981

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=e1ypm-M7_n" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=e1ypm-M7_n</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.20452/wiitm.2024.17894" target="_blank" >10.20452/wiitm.2024.17894</a>

Result language

angličtina

Original language name

Computed tomography-guided percutaneous biopsy in diagnosis of suspected metastatic renal cell carcinoma: which location is the most suitable?

Original language description

Introduction: Systemic targeted therapy options are commonly used in patients with metastatic renal cell carcinoma (mRCC). Histological verification is crucial for treatment of mRCC. Aim: Our aim was to evaluate an optimal location for percutaneous computed tomography-guided biopsy in a diagnosis of suspected mRCC. Materials and methods: A total of 138 percutaneous biopsies for tumors ranging from 21 to 133 mm in diameter (median, 72 mm) were carried out in 134 patients with suspected mRCC over a 5-year period. The biopsy location was variable, with kidney biopsy performed in 77 cases (55.8%), and other localizations (retroperitoneum, peritoneal cavity, liver, pelvis, pleural space, lung, mediastinum, chest or abdominal wall, and pancreas) in 61 cases (44.2%). Results: As many as 288 biopsies (97.1%), yielded true-positive results, and 4 procedures (2.9%) yielded histologically false-negative results that required confirmation through extended rebiopsy. RCC was the most common individual diagnosis (85.5%), with non-RCC histology verified in 14.5% of cases. In total, 32 complications (23.2%) were confirmed, 2 of which were pneumothoraces, 29 were minor bleeding that needed only conservative management, and 1 case required angiography and embolization for hemorrhage treatment. While no significant relationship between the biopsy success and lesion localization (renal vs other) was found (P = 0.13), the relationship between complication rate and biopsy localization (renal vs other) was significant (P = 0.01). Conclusions: Lesion localization (renal vs other) was not relevant to histological accuracy of the biopsies performed in patients with suspected mRCC. However, the biopsies of lesions outside the kidney had a lower complication rate.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30224 - Radiology, nuclear medicine and medical imaging

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Videosurgery and Other Miniinvasive Techniques

ISSN

1895-4588

e-ISSN

2299-0054

Volume of the periodical

19

Issue of the periodical within the volume

3

Country of publishing house

PL - POLAND

Number of pages

9

Pages from-to

361-369

UT code for WoS article

001414764400011

EID of the result in the Scopus database

2-s2.0-85215630209