Role of Intrauterine Infectious and Inflammatory Complications in the Development of Necrotizing Enterocolitis in a Newborn from Preterm Prelabor Rupture of Membranes' Gestation: A Retrospective Cohort Study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F25%3A10499774" target="_blank" >RIV/00179906:_____/25:10499774 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/25:10499774
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=JsKJr-cktc" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=JsKJr-cktc</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1159/000546257" target="_blank" >10.1159/000546257</a>
Alternative languages
Result language
angličtina
Original language name
Role of Intrauterine Infectious and Inflammatory Complications in the Development of Necrotizing Enterocolitis in a Newborn from Preterm Prelabor Rupture of Membranes' Gestation: A Retrospective Cohort Study
Original language description
Introduction: This study aimed to evaluate whether the presence of microbial invasion of the amniotic cavity (MIAC) and/or acute histological chorioamnionitis (HCA), as well as their subtypes, in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) is related to the subsequent development of necrotizing enterocolitis (NEC) in newborns from these pregnancies. Methods: This retrospective study included 295 women with singleton pregnancies complicated by PPROM between gestational ages 24+0 and 31+6 weeks who underwent transabdominal amniocentesis. MIAC was detected using a combination of cultivated and noncultivated methods. HCA was revealed by histopathological examination of the placenta. Only neonates with stage IIa of the modified Bell's criteria were considered to have NEC. Results: NEC developed in 3% (10/295) of newborns. There were no differences in the rates of MIAC (p = 0.33), HCA with the absence (p = 1.00) or presence of fetal inflammatory response (p = 0.52), and HCA with acute inflammation of the amnion (p = 0.20) between those who developed and did not develop NEC. Conclusion: Neither MIAC nor HCA was associated with the development of NEC in newborns from singleton pregnancies complicated by PPROM between 24+0 and 31+6 weeks of gestation.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30200 - Clinical medicine
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Fetal Diagnosis and Therapy
ISSN
1015-3837
e-ISSN
1421-9964
Volume of the periodical
52
Issue of the periodical within the volume
5
Country of publishing house
CH - SWITZERLAND
Number of pages
15
Pages from-to
468-482
UT code for WoS article
001516929500001
EID of the result in the Scopus database
2-s2.0-105009713946