Prophylactic Negative Pressure Therapy in Reducing the Risk of Sternal Wound Infection after Cardiac Surgery

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F25%3A10506754" target="_blank" >RIV/00179906:_____/25:10506754 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/25:10506754

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=DI2eNLcEY8" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=DI2eNLcEY8</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.33678/cor.2025.030" target="_blank" >10.33678/cor.2025.030</a>

Result language

angličtina

Original language name

Prophylactic Negative Pressure Therapy in Reducing the Risk of Sternal Wound Infection after Cardiac Surgery

Original language description

Background: Postoperative sternal wound infections and dehiscence are serious complications of cardiac surgery that increase the length of hospital stay and healthcare costs. Standard wound care may be insufficient for preventing these complications in high-risk patients. Methods: We conducted a prospective, randomized study comparing the efficacy of closed incisional negative pressure wound therapy (ciNPWT) using Prevena (study group) versus standard wound dressing (control group) in patients at high risk of sternal wound infections following cardiac surgery. Primary outcomes included the incidence of sternal wound infection at seven days and three months postoperatively, and length of hospital stay. Results: The study cohort comprised 80 patients (64 male, 16 female; mean age 65.4 years) randomized into two groups with 40 patients in each. At 7 days post-operation, there were four patients with sternal wound infection in the study group (10 %) and seven in the control group (17.5%) (p-value=0.52). At 3 months, deep wound infections were present in 1 patient in the study group (2.5%) and 2 in the control group (5%) (p = 1.00). Median length of hospital stay was comparable between the study (12 days) and control (11 days) groups (p-value = 0.75). Conclusions: Preventive negative pressure wound treatment showed a trend towards reducing the incidence of wound healing complications in high-risk patients following cardiac surgery, although the differences were not statistically significant. Further large-scale studies are warranted to establish the efficacy and cost--effectiveness of this preventive strategy.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Cor et Vasa

ISSN

0010-8650

e-ISSN

1803-7712

Volume of the periodical

67

Issue of the periodical within the volume

5

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

4

Pages from-to

572-575

UT code for WoS article

001618286800003

EID of the result in the Scopus database

2-s2.0-105023961653