How to Assess Environmental Etiological Factors of Mental Disorders: A Narrative Review Focused on Stress
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F25%3A10508029" target="_blank" >RIV/00179906:_____/25:10508029 - isvavai.cz</a>
Alternative codes found
RIV/61988987:17110/25:A2603D9W RIV/00216208:11150/25:10508029 RIV/61989592:15110/25:73633628 RIV/00098892:_____/25:10159646
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=F1VFxh8AKf" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=F1VFxh8AKf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
How to Assess Environmental Etiological Factors of Mental Disorders: A Narrative Review Focused on Stress
Original language description
Clarifying the etiology of mental disorders should lead to significant therapeutic and preventive measure improvements. Mental disorders are caused by genetic, epigenetic, and environmental factors. A valid assessment of environmental etiological factors is complicated due to a lack in methodologies. We aim to demonstrate how to optimally assess the environmental etiological factors with a special focus on stress. We searched the PubMed database up to December 2024 for relevant state-of-the-art references. The most frequently used stress assessment method involves self-reporting questionnaires. Blood or salivary cortisol, heart rate, respiratory rate, plethysmography readings, and electrodermal activity are biological markers of acute stress. Other biological markers such as hair and nail cortisol levels, telomere length, mitochondrial DNA copy number, and epigenetic markers are indicative of a history of stress. A quantitative prospective assessment of environmental etiological factors including their frequency, severity, total exposure length, timing, and possible accumulation is still needed. In addition, protective environmental factors of mental disorders should not be neglected.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30215 - Psychiatry
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neuroendocrinology Letters
ISSN
0172-780X
e-ISSN
2354-4716
Volume of the periodical
46
Issue of the periodical within the volume
6
Country of publishing house
SE - SWEDEN
Number of pages
12
Pages from-to
323-334
UT code for WoS article
001650136400002
EID of the result in the Scopus database
2-s2.0-105027399299