The importance of sentinel node biopsy and examination in malignant melanoma of the head and neck

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F25%3A10509484" target="_blank" >RIV/00179906:_____/25:10509484 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/25:10509484

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=055INCW88x" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=055INCW88x</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.48095/ccachp2025155" target="_blank" >10.48095/ccachp2025155</a>

Result language

angličtina

Original language name

The importance of sentinel node biopsy and examination in malignant melanoma of the head and neck

Original language description

Background: Malignant melanoma of the head and neck is a highly aggressive tumor with a significant risk of regional and distant metastases. Due to the complex anatomy and rich lymphatic drainage of this area, accurate and timely diagnosis and staging are essential for optimal treatment planning. The sentinel lymph node plays a key role in assessing tumor spread and staging. Materials and methods: A retrospective study was conducted on 26 patients with head and neck melanoma who underwent sentinel lymph node biopsy at our institution between 2017 and 2023. We evaluated the success rate of sentinel node localization, presence of metastases, and subsequent lymphadenectomy. Results: Sentinel lymph nodes were successfully identified in 23 patients; 5 had positive findings (3 macrometastases, 1 micrometastasis, 1 isolated tumor cells). Lymphadenectomy was indicated in patients with macrometastases, while follow up monitoring was preferred for micrometastases and isolated tumor cells. One patient experienced a complication after lymphadenectomy. Most patients with negative sentinel nodes remained disease-free during follow-up. Conclusion: Sentinel lymph node biopsy is a crucial tool for staging and treatment decision-making in head and neck malignant melanoma. The procedure&apos;s success depends on surgical expertise. Lymphadenectomy is indicated in cases of macrometastases, whereas micrometastases and isolated tumor cells warrant regular follow up. An individualized, multidisciplinary approach is essential.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

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OECD FORD branch

30204 - Oncology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta Chirurgiae Plasticae

ISSN

0001-5423

e-ISSN

1805-4404

Volume of the periodical

67

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

5

Pages from-to

155-159

UT code for WoS article

—

EID of the result in the Scopus database

2-s2.0-105031093084