MDM2 SNP309 does not associate with elevated MDM2 protein expression or breast cancer risk
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F08%3A%230000074" target="_blank" >RIV/00209805:_____/08:#0000074 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/08:00039782
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
MDM2 SNP309 does not associate with elevated MDM2 protein expression or breast cancer risk
Original language description
The incidence of SNP309 polymorphism in the promoter sequence of MDM2 determined in different tumor samples and compared to protein levels of MDM2 and p53. Neither the association between SNP309 and cancer risk, nor the responsibility of G allele for increased MDM2 or decreased of p53 protein levels in human primary breast tumors was shown.
Czech name
MDM2 SNP309 není spoje se zvýšenou expresí proteinu MDM2 nebo zvýšeným rizikem rakoviny prsu
Czech description
Byla sledována incidence polymorfismu SNP309 sekvence promotoru MDM2 v různých typech nádoru a hladina proteinů MDM2 a p53. Nebyla nalezena žádaná asociace mezi SNP309 a vyšším rizikem rakoviny ani vliv přítomnosti G alely na zvýšení nebo snížení hladinyproteinů MDM2 a p53 v primárních nádorech prsu.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NR8338" target="_blank" >NR8338: Functional analysis of the p53-dependent pathways in breast cancer: Integration of genomic and proteomic approaches using DNA-macroarray and SELDI-TOF mass spectrometry techniques</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2008
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Oncology
ISSN
0030-2414
e-ISSN
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Volume of the periodical
24
Issue of the periodical within the volume
1-2
Country of publishing house
CH - SWITZERLAND
Number of pages
4
Pages from-to
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UT code for WoS article
000256752300013
EID of the result in the Scopus database
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