MicroRNAs and their target gene networks in renal cell carcinoma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F11%3A%230000190" target="_blank" >RIV/00209805:_____/11:#0000190 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14740/11:00060083
Result on the web
<a href="http://ac.els-cdn.com/S0006291X11000386/1-s2.0-S0006291X11000386-main.pdf?_tid=c85ef621e2e3ec6eb25b9022c5bfc00b&acdnat=1335544954_c2004911aa3d46b1b475f42d9a079440" target="_blank" >http://ac.els-cdn.com/S0006291X11000386/1-s2.0-S0006291X11000386-main.pdf?_tid=c85ef621e2e3ec6eb25b9022c5bfc00b&acdnat=1335544954_c2004911aa3d46b1b475f42d9a079440</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.bbrc.2011.01.019" target="_blank" >10.1016/j.bbrc.2011.01.019</a>
Alternative languages
Result language
angličtina
Original language name
MicroRNAs and their target gene networks in renal cell carcinoma
Original language description
MicroRNAs (miRNAs) are non-protein-coding short single stranded RNAs in the size range 19-25 nucleotides that are associated with gene regulation at the transcriptional and translational level. Recent studies have proved that miRNAs play important rolesin a large number of biological processes, including cellular differentiation, proliferation, apoptosis. etc. Changes in their expression were found in a variety of human cancers, including renal cell carcinoma pathogenesis. Specific miRNA alterations were associated with key pathogenetic mechanisms of renal cell carcinoma like hypoxia or epithelial-mesenchymal transition. In this review, we summarize the current knowledge of miRNA functions in renal cell carcinoma with an emphasis on miRNAs potential to serve as a powerful biomarker of disease and a novel therapeutic target in oncology.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biochemical and biophysical research communications
ISSN
0006-291X
e-ISSN
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Volume of the periodical
405
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
4
Pages from-to
153-156
UT code for WoS article
000287627500001
EID of the result in the Scopus database
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