Cardiac toxicity of targeted therapies used in the treatment for solid tumours: a review
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F12%3A%230000374" target="_blank" >RIV/00209805:_____/12:#0000374 - isvavai.cz</a>
Result on the web
<a href="http://link.springer.com.proxy.mzk.cz/article/10.1007%2Fs12012-012-9164-0" target="_blank" >http://link.springer.com.proxy.mzk.cz/article/10.1007%2Fs12012-012-9164-0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s12012-012-9164-0" target="_blank" >10.1007/s12012-012-9164-0</a>
Alternative languages
Result language
angličtina
Original language name
Cardiac toxicity of targeted therapies used in the treatment for solid tumours: a review
Original language description
Cardiotoxicity associated with conventional cytostatics is a known phenomenon and is related to their general cytotoxic effects. This damage to the myocardium is usually irreversible. Despite the attempts to optimize safety profile of targeted anticancerdrugs during their development, evidence shows that these new treatment modalities also have cardiotoxic potential or may adversely affect vascular system. Over the last years, a significant number of these agents have been introduced in medical practice. Arterial hypertension, arrhythmias, left ventricular dysfunction and a heart failure are the most frequent cardiovascular adverse effects of targeted anticancer agents, but this toxicity seems to be reversible. To enable early interventions and to minimize these cardiovascular adverse effects, health care professionals have to be well-informed and familiar with the safety profiles of the drugs they administered, the patient's cardiovascular condition and co-morbidities, and they must
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cardiovascular toxicology
ISSN
1530-7905
e-ISSN
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Volume of the periodical
12
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
17
Pages from-to
191-207
UT code for WoS article
000306739100001
EID of the result in the Scopus database
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