Everolimus-related unilateral abdominal lymphedema in a renal cancer patient: A case report

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F20%3A00078469" target="_blank" >RIV/00209805:_____/20:00078469 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/20:00117214

Result on the web

<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571978/" target="_blank" >https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571978/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/MD.0000000000022634" target="_blank" >10.1097/MD.0000000000022634</a>

Result language

angličtina

Original language name

Everolimus-related unilateral abdominal lymphedema in a renal cancer patient: A case report

Original language description

Rationale: Unilateral manifestation of lymphedema during everolimus therapy has been described only rarely, mostly in transplant recipients. Patient concerns: We report the first case of a patient who developed unilateral abdominal lymphedema, during a short period of everolimus treatment for renal cancer. Diagnosis: The abdominal asymmetry occurred only on the right side of the abdomen, neither ultrasound nor CT scan detected ascites but showed enlargement of the abdominal wall. The Naranjo Adverse Drug Reaction Probability scale was evaluated, in this case, a score of 6 indicated a probable adverse reaction to everolimus. Interventions: Discontinuation of everolimus therapy led to immediate alleviation and reduction of the lymphedema, with worsening once again after initiating retreatment with everolimus at a reduced dose. Outcomes: The patient&apos;s lymphedema recovered after discontinuation of everolimus. Lessons: This rare case demonstrates the importance of the selection of mammalian target of rapamycin inhibitors using caution, especially for patients with a high risk of developing lymphedema.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30204 - Oncology

Project

<a href="/en/project/LM2018128" target="_blank" >LM2018128: Czech National Node of the European Clinical Research Infrastructure Network</a><br>

Continuities

—

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Medicine (Baltimore)

ISSN

0025-7974

e-ISSN

—

Volume of the periodical

99

Issue of the periodical within the volume

42

Country of publishing house

US - UNITED STATES

Number of pages

4

Pages from-to

"e22634"

UT code for WoS article

000589394700033

EID of the result in the Scopus database

2-s2.0-85094221345