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Update on the Role of Rifaximin in Digestive Diseases

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F23%3A00079205" target="_blank" >RIV/00209805:_____/23:00079205 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/23:00131030

  • Result on the web

    <a href="https://jgld.ro/jgld/index.php/jgld/article/view/4871" target="_blank" >https://jgld.ro/jgld/index.php/jgld/article/view/4871</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.15403/jgld-4871" target="_blank" >10.15403/jgld-4871</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Update on the Role of Rifaximin in Digestive Diseases

  • Original language description

    Various environmental factors affecting the human microbiota may lead to gut microbial imbalance and to the development of pathologies. Alterations of gut microbiota have been firmly implicated in digestive diseases such as hepatic encephalopathy, irritable bowel syndrome and diverticular disease. However, while these three conditions may all be related to dysfunction of the gut-liver-brain axis, the precise pathophysiology appears to differ somewhat for each. Herein, current knowledge on the pathophysiology of hepatic encephalopathy, irritable bowel syndrome, and diverticular disease are reviewed, with a special focus on the gut microbiota modulation associated with these disorders during therapy with rifaximin. In general, the evidence for the efficacy of rifaximin in hepatic encephalopathy appears to be well consolidated, although it is less supported for irritable bowel syndrome and diverticular disease. We reviewed current clinical practice for the management of these clinical conditions and underlined the desirability of more real-world studies to fully understand the potential of rifaximin in these clinical situations and obtain even more precise indications for the use of the drug.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30219 - Gastroenterology and hepatology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of gastrointestinal and liver diseases

  • ISSN

    1841-8724

  • e-ISSN

    1842-1121

  • Volume of the periodical

    32

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    RO - ROMANIA

  • Number of pages

    18

  • Pages from-to

    92-109

  • UT code for WoS article

    000972987600016

  • EID of the result in the Scopus database

    2-s2.0-85151328387