Cytokinin arabinosides show increased efficacy in priming tomato immunity and inhibiting the fungal phytopathogen B. cinerea
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F25%3A00080443" target="_blank" >RIV/00209805:_____/25:00080443 - isvavai.cz</a>
Alternative codes found
RIV/61389030:_____/25:00641187 RIV/61989592:15310/25:73632016
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S2667064X25003239" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2667064X25003239</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.stress.2025.101055" target="_blank" >10.1016/j.stress.2025.101055</a>
Alternative languages
Result language
angličtina
Original language name
Cytokinin arabinosides show increased efficacy in priming tomato immunity and inhibiting the fungal phytopathogen B. cinerea
Original language description
Cytokinins (CKs) regulate numerous biological processes in plants, and are involved in plant growth and development as well as responses to biotic and abiotic stresses. Although CKs have been reported to prime plant immunity, thus far, research on CK hormopriming has focused on classical synthetic CKs such as kinetin or 6-benzylaminopurine (BAP). Here, we show that synthetic aromatic CK derivatives-specifically, 3-methoxy-6-benzylaminopurine-9-arabinosides-effectively induce immune responses and promote resistance to Botrytis cinerea in tomato (Solanum lycopersicum) primarily via a salicylic acid (SA)-dependent mechanism. Additionally, like 6- BAP, these compounds directly inhibit B. cinerea. Transcriptomic analyses of B. cinerea treated with CK arabinosides revealed significant changes in expressed gene profiles, notably in pathways associated with sugar metabolism. Unlike classical CKs, CK arabinosides do not alleviate growth inhibition under sugar-limited conditions, contributing to their stronger antifungal effects. Furthermore, CK arabinosides induce tomato immune responses more robustly than classical CKs, yet without activating canonical cytokinin signaling pathways, likely owing to their exceptional chemical stability which prevents release of the free active CK base, and due to their inability to directly bind CK receptors. Altogether, our findings suggest that CK arabinosides act via a dual mechanism-immune priming and direct pathogen inhibition-and hold promise as next-generation hormopriming agents for sustainable crop protection.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10611 - Plant sciences, botany
Result continuities
Project
<a href="/en/project/EH22_008%2F0004581" target="_blank" >EH22_008/0004581: TowArds Next GENeration Crops (TANGENC)</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Plant stress
ISSN
2667-064X
e-ISSN
2667-064X
Volume of the periodical
18
Issue of the periodical within the volume
December 2025
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
12
Pages from-to
101055
UT code for WoS article
001594551300001
EID of the result in the Scopus database
2-s2.0-105018178878