Defective cytotoxicity of T lymphocytes in myelodysplastic syndrome

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F09%3A5784" target="_blank" >RIV/00216208:11110/09:5784 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/09:5784 RIV/00023736:_____/09:00008202

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Defective cytotoxicity of T lymphocytes in myelodysplastic syndrome

Original language description

Conclusion: The presumed autoaggressive T cells were not confirmed in myelodysplastic syndrome (MDS) in our experimental arragement. Alloreactivity studies demonstrated the impairment of effector cytotoxic phase of cell-mediated immunological reaction inMDS, namely in refractory anemia. The significance of our finding of defective cytotoxicity for pathogenesis, clinical course, and even for therapy is discussed together with other immunologial defects reported so far.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Experimental Hematology

ISSN

0301-472X

e-ISSN

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Volume of the periodical

37

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

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UT code for WoS article

000263819200008

EID of the result in the Scopus database

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