Remosomes: RSC generated non-mobilized particles with approximately 180 bp DNA loosely associated with the histone octamer
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F10%3A6355" target="_blank" >RIV/00216208:11110/10:6355 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Remosomes: RSC generated non-mobilized particles with approximately 180 bp DNA loosely associated with the histone octamer
Original language description
Intermediate products generated during the process of chromatin remodeling by RSC complex, the so-called remosomes, were identified by high-resolution cryo-electron microscopy and molecular biology methods. This remosome (remodeled nucleosome) is a metastable product of the first phase of the remodeling process. In contrast to original nucleosome, about 35 bp of DNA are associated with histone octamer, which results in creation of a DNA loop that dynamically moves around the perimeter of the octamer andallows thus access to originally inaccessible nucleosomal DNA. The measurement of the DNA accessibility by restricition enzymes showed that nucleosomal DNA was about 5x more accessible in comparison to its original state. Erratum in: Proc Natl Acad SciU S A. 2010 Apr 27;107(17):8041
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Proceedings of the National Academy of Sciences of the USA
ISSN
0027-8424
e-ISSN
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Volume of the periodical
107
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
6
Pages from-to
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UT code for WoS article
000274296300026
EID of the result in the Scopus database
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