Glycine serum level in schizophrenia: Relation to negative symptoms

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F10%3A7321" target="_blank" >RIV/00216208:11110/10:7321 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/10:10051972 RIV/00179906:_____/10:10051972 RIV/00064165:_____/10:7321
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Glycine serum level in schizophrenia: Relation to negative symptoms
Original language description
We hypothesized that glycine serum levels might be associated with intensity of negative symptoms in schizophrenia. In our study we found mean glycine serum levels to be significantly lower in patients than in controls. That difference was only caused byfindings in the male study population. Glycine serum levels were negatively associated with intensity of negative symptoms assessed by the PANSS negative subscale and the SANS total scores in the patients. These data suggest a possible implication of NMDA receptor dysfunction in the pathogenesis of negative symptoms in schizophrenia.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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