Presence of Borrelia burgdorferi in endomyocardial biopsies in patients with new-onset unexplained dilated cardiomyopathy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F10%3A7903" target="_blank" >RIV/00216208:11110/10:7903 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/10:7903

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Presence of Borrelia burgdorferi in endomyocardial biopsies in patients with new-onset unexplained dilated cardiomyopathy

Original language description

Infectious and autoimmune mechanisms, together with genetic abnromalities, have been reported as three majoc cause of dilated cardiomyopathy. Czech republic represents a highly endemic area for Lyme disease. In endomyocardial biopises taken from 39 consecutive patients with new-onset unexplained dilated cardiomyopathy we have found Borrelia burgdorferi genom or particles in 8 subjects (21%). The treatment with intravenous ceftriaxone led in positively tested patients to significant improvement in left ventricular structural and functional abnormalities and heart failure symptoms, respectively. Borrelia burgdorferi infection thus probably represents an important and treatable cause on new-onset dilated cardiomyopathy in endemic regions for Lyme disease.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Medical microbiology and immunology

ISSN

0300-8584

e-ISSN

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Volume of the periodical

199

Issue of the periodical within the volume

2

Country of publishing house

DE - GERMANY

Number of pages

5

Pages from-to

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UT code for WoS article

000276661300009

EID of the result in the Scopus database

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