Treatment of consecutive patients with chronic myeloid leukaemia in the cooperating centres from the Czech Republic and the whole of Slovakia after 2000-a report from the population-based CAMELIA Registry

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F11%3A11318" target="_blank" >RIV/00216208:11110/11:11318 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/11:00052700 RIV/00216208:11120/11:00003394 RIV/00216208:11150/11:10107290 RIV/61989592:15110/11:10223260 and 2 more

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Treatment of consecutive patients with chronic myeloid leukaemia in the cooperating centres from the Czech Republic and the whole of Slovakia after 2000-a report from the population-based CAMELIA Registry

Original language description

Background: Most results on the treatment of chronic myeloid leukaemia (CML) with imatinib were obtained from clinical trials that may differ from the routine practice. We report the results of treatment of consecutive patients with CML at ten major centres during 2000-2008. Patients and methods: Data reporting was retrospective in 2000-2004 and prospective from 2005 on. A total of 661 patients [301 women and 360 men; median age 51 (range, 15-83)] with Ph + CML were registered. The median follow-up was46.1 months (0-122.2). Results: Most patients were treated with first-(379; 57.3%) or second-line (193; 29.2%) imatinib; some of the patients underwent allogeneic hematopoietic stem cell transplantation (AHSCT) (83; 12.6%), but 6.1% were treated with other modalities [40 patients; median age 66 (range, 32-83)]. The probability of overall survival (OS) at 5 years, according to Kaplan and Meier, was 88.9%, 77.5% and 68.7% for chronic-phase patients treated with first-line imatinib, second-

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Journal of Haematology

ISSN

0902-4441

e-ISSN

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Volume of the periodical

87

Issue of the periodical within the volume

2

Country of publishing house

DK - DENMARK

Number of pages

12

Pages from-to

157-168

UT code for WoS article

000292778800008

EID of the result in the Scopus database

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