Clinical features of childhood narcolepsy. Can cataplexy be foretold?

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F11%3A8887" target="_blank" >RIV/00216208:11110/11:8887 - isvavai.cz</a>
Alternative codes found
RIV/00023001:_____/11:00002476 RIV/00064165:_____/11:8887
Result on the web
<a href="http://dx.doi.org/10.1016/j.ejpn.2011.01.008" target="_blank" >http://dx.doi.org/10.1016/j.ejpn.2011.01.008</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Clinical features of childhood narcolepsy. Can cataplexy be foretold?
Original language description
The aim of our study was to evaluate clinical and polysomnographic parameters to verify if cataplexy appearing later in life can be foretold. Methods: 30 patients (12 boys), who contracted narcolepsy before the age of 18, were enrolled. All underwent clinical examination, nocturnal polysomnography (PSG), multiple sleep latency test (MSLT), HLA-DQB1*0602 testing and, most of them Epworth Sleepiness Scale (ESS) rating. The Mann Whitney rank and Fisher's tests were used for statistical analysis. Results: Narcolepsy without cataplexy (NwC) was diagnosed in 40% of the patients. The mean age at the first symptoms was 14.0 +/- 3.0, at diagnosis 15.6 +/- 3.1 years. Narcolepsy was accompanied by hypnagogic hallucinations in 15 and sleep paralysis in 12 patients. Conclusion: Narcolepsy in childhood leaves very little scope for the prediction of cataplexy later in life.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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