The role of monototal in the primary diagnosis, prognosis and follow-up of patients with non-small cell lung cancer (NSCLC)

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F11%3A9399" target="_blank" >RIV/00216208:11110/11:9399 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11140/11:10103150 RIV/00064165:_____/11:9399

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The role of monototal in the primary diagnosis, prognosis and follow-up of patients with non-small cell lung cancer (NSCLC)

Original language description

A new cytokeratin tumor marker, MonoTotal was studied in lung cancer, the most common cause of cancer mortality worldwide. In non-small cell lung cancer (NSCLC) patients MonoTotal serum levels and their relationship to the tumor stage, histological subtype, early relapse and cancer-related death were evaluated. Patients and Methods: MonoTotal serum levels were studied, using immunoradiometric assay in a group of 93 patients with newly diagnosed NSCLC undergoing radical surgery, and were compared to those with benign lung diseases. Results: A diagnostic power of MonoTotal in distinguishing patients with NSCLC from benign lung diseases was demonstrated. Higher levels of Mono Total were associated with advanced stages of squamous cell carcinoma and therewas a positive correlation of marker with tumor size. Marker levels showed significant relation to disease-free survival and overall survival. Conclusion: MonoTotal seems to be a potentially very interesting serum marker that, in conjunct

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Anticancer Research

ISSN

0250-7005

e-ISSN

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Volume of the periodical

31

Issue of the periodical within the volume

9

Country of publishing house

GR - GREECE

Number of pages

6

Pages from-to

3107-3112

UT code for WoS article

000293357700060

EID of the result in the Scopus database

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