Subthalamic Nucleus Stimulation Affects Incentive Salience Attribution in Parkinson's Disease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F11%3A9461" target="_blank" >RIV/00216208:11110/11:9461 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21230/11:00183241 RIV/00064165:_____/11:9461
Result on the web
<a href="http://dx.doi.org/10.1002/mds.23880" target="_blank" >http://dx.doi.org/10.1002/mds.23880</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Subthalamic Nucleus Stimulation Affects Incentive Salience Attribution in Parkinson's Disease
Original language description
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) can induce nonmotor side effects such as behavioral and mood disturbances or body weight gain in Parkinson's disease (PD) patients. We hypothesized that some of these problems could be relatedto an altered attribution of incentive salience (ie, emotional relevance) to rewarding and aversive stimuli. Twenty PD patients (all men; mean age +/- SD, 58.3 +/- 6 years) in bilateral STN DBS switched ON and OFF conditions and 18 matched controls rated pictures selected from the International Affective Picture System according to emotional valence (unpleasantness/pleasantness) and arousal on 2 independent visual scales ranging from 1 to 9. Eighty-four pictures depicting primary rewarding (erotica andfood) and aversive fearful (victims and threat) and neutral stimuli were selected for this study. In the STN DBS ON condition, the PD patients attributed lower valence scores to the aversive pictures compared with the OFF condition (P <
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA309%2F09%2F1145" target="_blank" >GA309/09/1145: Mechanisms of deep brain stimulation: Role of the subthalamus in motor, visual and affective processing</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Movement Disorders
ISSN
0885-3185
e-ISSN
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Volume of the periodical
26
Issue of the periodical within the volume
12
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
2260-2266
UT code for WoS article
000296610900022
EID of the result in the Scopus database
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