Abnormal Activity in the Precuneus during Time Perception in Parkinson's Disease: An fMRI Study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A11490" target="_blank" >RIV/00216208:11110/12:11490 - isvavai.cz</a>

Alternative codes found

RIV/68407700:21230/12:00187918 RIV/00064165:_____/12:11490

Result on the web

<a href="http://dx.doi.org/10.1371/journal.pone.0029635" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0029635</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Abnormal Activity in the Precuneus during Time Perception in Parkinson's Disease: An fMRI Study

Original language description

The aim of the present study was to explore the neurophysiologic correlates of this deficit. We performed functional magnetic resonance imaging on twelve PD patients while they were performing a time reproduction task (TRT). The TRT consisted of an encoding phase (during which visual stimuli of durations from 5s to 16.6s, varied at 8 levels were presented) and a reproduction phase (during which interval durations were reproduced by a button pressing). Patients were scanned twice, once while on their DAmedication (ON condition) and once after medication withdrawal (OFF condition). Differences in Blood-Oxygenation-Level-Dependent (BOLD) signal in ON and OFF conditions were evaluated. The time course of activation in the brain areas with different BOLD signal was plotted. There were no significant differences in the behavioral results, but a trend toward overestimation of intervals <= 11.9s and underestimation of intervals >= 14.1s in the OFF condition (p < 0.088). During the reproductio

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

PLoS One

ISSN

1932-6203

e-ISSN

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Volume of the periodical

7

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

"nestrankovano"

UT code for WoS article

000301188800022

EID of the result in the Scopus database

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