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Decrease in heart adrenoceptor gene expression and receptor number as compensatory tool for preserved heart function and biological rhythm in M-2 KO animals

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A11500" target="_blank" >RIV/00216208:11110/12:11500 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1007/s00210-012-0800-9" target="_blank" >http://dx.doi.org/10.1007/s00210-012-0800-9</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Decrease in heart adrenoceptor gene expression and receptor number as compensatory tool for preserved heart function and biological rhythm in M-2 KO animals

  • Original language description

    We investigated the changes in gene expression, receptor number, echocardiography, muscarinic/adrenergic agonist/antagonist changes in heart rate (HR) and HR biorhythm in M-2 KO mice (mice lacking the main cardioinhibitory receptors) in the left ventricle (LV) and right ventricle (RV). We can conclude that although the main cardioinhobitory receptors are not present in the heart, the function is not much affected.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA309%2F09%2F0406" target="_blank" >GA309/09/0406: Muscarinic receptor regulation</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Naunyn-Schmiedebergs Archives of Pharmacology

  • ISSN

    0028-1298

  • e-ISSN

  • Volume of the periodical

    385

  • Issue of the periodical within the volume

    12

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    13

  • Pages from-to

    1161-1173

  • UT code for WoS article

    000310962000002

  • EID of the result in the Scopus database