Decrease in heart adrenoceptor gene expression and receptor number as compensatory tool for preserved heart function and biological rhythm in M-2 KO animals
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A11500" target="_blank" >RIV/00216208:11110/12:11500 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s00210-012-0800-9" target="_blank" >http://dx.doi.org/10.1007/s00210-012-0800-9</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Decrease in heart adrenoceptor gene expression and receptor number as compensatory tool for preserved heart function and biological rhythm in M-2 KO animals
Original language description
We investigated the changes in gene expression, receptor number, echocardiography, muscarinic/adrenergic agonist/antagonist changes in heart rate (HR) and HR biorhythm in M-2 KO mice (mice lacking the main cardioinhibitory receptors) in the left ventricle (LV) and right ventricle (RV). We can conclude that although the main cardioinhobitory receptors are not present in the heart, the function is not much affected.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA309%2F09%2F0406" target="_blank" >GA309/09/0406: Muscarinic receptor regulation</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Naunyn-Schmiedebergs Archives of Pharmacology
ISSN
0028-1298
e-ISSN
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Volume of the periodical
385
Issue of the periodical within the volume
12
Country of publishing house
US - UNITED STATES
Number of pages
13
Pages from-to
1161-1173
UT code for WoS article
000310962000002
EID of the result in the Scopus database
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