Weight Gain Is Associated with Medial Contact Site of Subthalamic Stimulation in Parkinson's Disease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A11630" target="_blank" >RIV/00216208:11110/12:11630 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/12:11630 RIV/00023884:_____/12:00007610
Result on the web
<a href="http://dx.doi.org/10.1371/journal.pone.0038020" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0038020</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Weight Gain Is Associated with Medial Contact Site of Subthalamic Stimulation in Parkinson's Disease
Original language description
The aim of our study was to assess changes in body-weight in relation to active electrode contact position in the subthalamic nucleus. Regular body weight measurements were done in 20 patients with advanced Parkinson's disease within a period of 18 months after implantation. T1-weighted (1.5T) magnetic resonance images were used to determine electrode position in the subthalamic nucleus and the Unified Parkinson's disease rating scale (UPDRS-III) was used for motor assessment. The distance of the contacts from the wall of the third ventricle in the mediolateral direction inversely correlated with weight gain (r = -0.55, p<0.01) and with neurostimulation-related motor condition expressed as the contralateral hemi-body UPDRS-III (r = -0.42, p<0.01). Patients with at least one contact within 9.3 mm of the wall experienced significantly greater weight gain (9.4+/-(SD) 4.4 kg, N = 11) than those with both contacts located laterally (3.9+/-2.7 kg, N = 9) (p<0.001). The position of the active
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PLoS One
ISSN
1932-6203
e-ISSN
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Volume of the periodical
7
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
"nestrankovano"
UT code for WoS article
000305353400069
EID of the result in the Scopus database
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