Severe cobalt intoxication following hip replacement revision: Clinical features and outcome

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A11946" target="_blank" >RIV/00216208:11110/12:11946 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/12:11946

Result on the web

<a href="http://dx.doi.org/10.3109/15563650.2012.670244" target="_blank" >http://dx.doi.org/10.3109/15563650.2012.670244</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Severe cobalt intoxication following hip replacement revision: Clinical features and outcome

Original language description

Context. Cobalt intoxication has become more frequent due to the wide use of metal hip implants. Case details. A 56-year-old male patient underwent total hip prosthesis, with a ceramics-on-ceramics implant. Almost 3 years later, it was replaced by metalimplant containing cobalt, chromium, and titanium. He developed weight loss, heart, thyroid, and neurological toxicity, with severe hearing loss. He was treated with 2,3-dimercaptopropane-1-sulfonate (DMPS), and cobalt excretion increased. Clinical symptoms apart from deafness gradually resolved. Conclusion. We report significant cobalt poisoning from a damaged hip replacement with cobalt containing implant and a slow abrasion of the metal by residual ceramic particles. Chelation therapy resulted in apparent benefit.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FE - Other fields of internal medicine

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Clinical Toxicology

ISSN

1556-3650

e-ISSN

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Volume of the periodical

50

Issue of the periodical within the volume

4

Country of publishing house

US - UNITED STATES

Number of pages

4

Pages from-to

262-265

UT code for WoS article

000302024600006

EID of the result in the Scopus database

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