NEUROPEPTIDE OXYTOCIN IS ALSO SYNTHESIZED IN THE HEART UNDER BASAL AS WELL AS STRESS CONDITIONS AND FUNCTIONS AS A NEW CARDIOVASCULAR HORMONE

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A12386" target="_blank" >RIV/00216208:11110/12:12386 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
NEUROPEPTIDE OXYTOCIN IS ALSO SYNTHESIZED IN THE HEART UNDER BASAL AS WELL AS STRESS CONDITIONS AND FUNCTIONS AS A NEW CARDIOVASCULAR HORMONE
Original language description
Our results contribute to the idea of oxytocin functioning as a cardiovascular hormone. Expression of OTR mRNA and immunohistochemical detection of OTR in all heart compartments indicate that oxytocin system plays an important regulatory role in the cardiovascular system both under basal and stress conditions. The distribution of oxytocin and its receptors in the heart, and in some cases their colocalization with nuclei are new findings, which can explain some controversial findings like quantitative discrepancy in expression of OTR mRNA and expression of OTR receptor protein. These findings require further studies and it can be expected that they will help to find target structures for therapeutic interventions.
Czech name
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Czech description
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Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
9th International Medical Postgraduate Conference New Frontiers in the Research of PhD Students
ISBN
978-80-260-3373-8
ISSN
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e-ISSN
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Number of pages
4
Pages from-to
86-89
Publisher name
Charles University in Prague,Faculty of Medicine in Hradec Králové
Place of publication
Hradec Králové
Event location
Hradec Králové, ČR
Event date
Nov 22, 2012
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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