Is screening for hereditary thrombophilia indicated in first early pregnancy loss?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A12620" target="_blank" >RIV/00216208:11110/12:12620 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/12:12620

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Is screening for hereditary thrombophilia indicated in first early pregnancy loss?

Original language description

The aim of the study was to evaluate the importance of screening for thrombophilic mutations after the first early pregnancy loss. Thrombophilic mutations were examinated in a sample of 100 women with at least one miscarriage. We detected prevalence of factor V and II mutation of 9% and 3%, respectively. Single MTHFR mutation was found in 59% and double heterozygous MTHFR mutation in 23% of cases. No mutation was present in only 6% of the study group. Heterozygous mutations of factor V occurred 1.8 times more frequently in our study group compared to the general Czech women population. Also, the frequency of factor II mutation was 1.5-3 times higher.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FK - Gynaecology and obstetrics

OECD FORD branch

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Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neuroendocrinology Letters

ISSN

0172-780X

e-ISSN

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Volume of the periodical

33

Issue of the periodical within the volume

1

Country of publishing house

SE - SWEDEN

Number of pages

5

Pages from-to

76-80

UT code for WoS article

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EID of the result in the Scopus database

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