Keratoconus in 18 pairs of twins
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A12644" target="_blank" >RIV/00216208:11110/12:12644 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1111/j.1755-3768.2012.02448.x" target="_blank" >http://dx.doi.org/10.1111/j.1755-3768.2012.02448.x</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Keratoconus in 18 pairs of twins
Original language description
The study describes the concordance of keratoconus in 18 sets of twins. Thirteen monozygotic (MZ) and five dizygotic (DZ) pairs of twins were identified during an investigation of familial keratoconus. The zygosity of same sex twins was confirmed by 16 forensic microsatellite markers. All of the MZ twins and four of the five DZ twins were concordant for keratoconus but with differences in age of onset and severity of disease. The results support the currently accepted hypothesis of an important geneticcontribution towards the pathogenesis of keratoconus, but suggest that there is also an environmental effect on the expression of disease.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Acta Ophthalmologica
ISSN
1755-375X
e-ISSN
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Volume of the periodical
90
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
"e482"-"e486"
UT code for WoS article
000308079900011
EID of the result in the Scopus database
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