Stress and strain adaptation in load-dependent remodeling of the embryonic left ventricle
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10188756" target="_blank" >RIV/00216208:11110/13:10188756 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s10237-012-0461-0" target="_blank" >http://dx.doi.org/10.1007/s10237-012-0461-0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10237-012-0461-0" target="_blank" >10.1007/s10237-012-0461-0</a>
Alternative languages
Result language
angličtina
Original language name
Stress and strain adaptation in load-dependent remodeling of the embryonic left ventricle
Original language description
Altered pressure in the developing left ventricle (LV) results in altered morphology and tissue material properties. Mechanical stress and strain may play a role in the regulating process. This study showed that confocal microscopy, three-dimensional reconstruction, and finite element analysis can provide a detailed model of stress and strain in the trabeculated embryonic heart. The method was used to test the hypothesis that end-diastolic strains are normalized after altered loading of the LV during the stages of trabecular compaction and chamber formation. Stage-29 chick LVs subjected to pressure overload and underload at stage 21 were reconstructed with full trabecular morphology from confocal images and analyzed with finite element techniques. Measured material properties and intraventricular pressures were specified in the models. The results show volume-weighted end-diastolic von Mises stress and strain averaging 50-82 % higher in the trabecular tissue than in the compact wall. T
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EA - Morphology and cytology
OECD FORD branch
—
Result continuities
Project
—
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomechanics and Modeling in Mechanobiology
ISSN
1617-7959
e-ISSN
—
Volume of the periodical
12
Issue of the periodical within the volume
5
Country of publishing house
DE - GERMANY
Number of pages
15
Pages from-to
1037-1051
UT code for WoS article
000324378900013
EID of the result in the Scopus database
—