Precise assessment of noncompliance with the antihypertensive therapy in patients with resistant hypertension using toxicological serum analysis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10189066" target="_blank" >RIV/00216208:11110/13:10189066 - isvavai.cz</a>
Alternative codes found
RIV/00023001:_____/13:00058774 RIV/00064165:_____/13:10189066
Result on the web
<a href="http://dx.doi.org/10.1097/HJH.0b013e3283652c61" target="_blank" >http://dx.doi.org/10.1097/HJH.0b013e3283652c61</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/HJH.0b013e3283652c61" target="_blank" >10.1097/HJH.0b013e3283652c61</a>
Alternative languages
Result language
angličtina
Original language name
Precise assessment of noncompliance with the antihypertensive therapy in patients with resistant hypertension using toxicological serum analysis
Original language description
Background:The aim of our study was to assess the prevalence of pseudo-resistance caused by noncompliance with treatment among patients with severe resistant hypertension and to analyze the contributing factors.Method:Three hundred and thirty-nine patients (195 men) with resistant essential hypertension were studied. The first group consisted of 176 patients admitted for hospitalization for exclusion of a secondary cause to our hypertension centre (103 men); the second one consisted of 163 out-patients(92 men) investigated for the first time in an out-patient hypertension clinic. Unplanned blood sampling for assessment of serum antihypertensive drug concentrations by means of liquid chromatography-mass spectrometry was performed in all patients.Results:Our main finding is a surprisingly low compliance with drug treatment in out-patients with resistant hypertension (23% partially noncompliant and 24% totally noncompliant - in total, 47% prevalence of noncompliance). Eighty-one percent
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT14155" target="_blank" >NT14155: Effect of the specific treatment of primary aldosteronism on subclinical organ damage regression</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Hypertension
ISSN
0263-6352
e-ISSN
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Volume of the periodical
31
Issue of the periodical within the volume
12
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
2455-2461
UT code for WoS article
000326946800020
EID of the result in the Scopus database
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