Serum Levels of Matrix Metalloproteinases 2 and 9 in Patients with Acute Myocardial Infarction
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10189655" target="_blank" >RIV/00216208:11110/13:10189655 - isvavai.cz</a>
Alternative codes found
RIV/67985807:_____/13:00425961 RIV/00216208:11310/13:10189655
Result on the web
<a href="http://fb.cuni.cz/file/5699/FB2013A0026.pdf" target="_blank" >http://fb.cuni.cz/file/5699/FB2013A0026.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Serum Levels of Matrix Metalloproteinases 2 and 9 in Patients with Acute Myocardial Infarction
Original language description
The myocardial extracellular matrix plays an important role in maintaining the structural and functional integrity of the heart and is centrally involved in post-myocardial infarction repair processes. We analysed some genetic and proteomic aspects thatcould play an important role in the development of myocardial infarction. Matrix metalloproteinases are enzymes that contribute strongly to the degradation of extracellular matrix components. In this study the serological levels of MMP-2 and MMP-9 were investigated using immunological testing in 34 patients with myocardial infarction and 34 matched control subjects. The serum levels of WIMPs were determined by ELISA. Changes in serum levels were characterized within 24 h and after 6 months post myocardial infarction. Significantly higher levels of MMP-2 (299.47 +/- 117.61 ng/ml) and MMP-9 (93.56 +/- 53.74 ng/ml) were determined in patients with myocardial infarction compared to the controls, in both cases P < 0.001. MMP-9 levels decreas
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
<a href="/en/project/1M06014" target="_blank" >1M06014: Centre of Biomedical Informatics</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Folia Biologica
ISSN
0015-5500
e-ISSN
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Volume of the periodical
59
Issue of the periodical within the volume
5
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
7
Pages from-to
181-187
UT code for WoS article
000327577300002
EID of the result in the Scopus database
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