The impact of rapid weight loss on oxidative stress markers and the expression of the metabolic syndrome in obese individuals

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10190836" target="_blank" >RIV/00216208:11110/13:10190836 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/13:10190836

Result on the web

<a href="http://dx.doi.org/10.1155/2013/729515" target="_blank" >http://dx.doi.org/10.1155/2013/729515</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/2013/729515" target="_blank" >10.1155/2013/729515</a>

Result language

angličtina

Original language name

The impact of rapid weight loss on oxidative stress markers and the expression of the metabolic syndrome in obese individuals

Original language description

Objective. Obesity is linked with a state of increased oxidative stress, which plays an important role in the etiology of atherosclerosis and type 2 diabetes mellitus. The aim of our study was to evaluate the effect of rapid weight loss on oxidative stress markers in obese individuals with metabolic syndrome (MetS). Design and Methods. We measured oxidative stress markers in 40 obese subjects with metabolic syndrome (MetS+), 40 obese subjects without metabolic syndrome (MetSMINUS SIGN ), and 20 lean controls (LC) at baseline and after three months of very low caloric diet. Results. Oxidized low density lipoprotein (ox-LDL) levels decreased by 12% in MetS+ subjects, associated with a reduction in total cholesterol (TC), even after adjustment for age andsex. Lipoprotein associated phospholipase A2 (Lp-PLA2) activity decreased by 4.7% in MetS+ subjects, associated with a drop in LDL-cholesterol (LDL-C), TC, and insulin levels. Multivariate logistic regression analysis showed that a model

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Obesity [online]

ISSN

2090-0716

e-ISSN

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Volume of the periodical

2013

Issue of the periodical within the volume

December 19

Country of publishing house

US - UNITED STATES

Number of pages

10

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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