Selecting deep brain stimulation or infusion therapies in advanced Parkinson's disease: an evidence-based review

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10191805" target="_blank" >RIV/00216208:11110/13:10191805 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1007/s00415-012-6798-6" target="_blank" >http://dx.doi.org/10.1007/s00415-012-6798-6</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00415-012-6798-6" target="_blank" >10.1007/s00415-012-6798-6</a>

Result language

angličtina

Original language name

Selecting deep brain stimulation or infusion therapies in advanced Parkinson's disease: an evidence-based review

Original language description

Motor complications in Parkinson's disease (PD) result from the short half-life and irregular plasma fluctuations of oral levodopa. When strategies of providing more continuous dopaminergic stimulation by adjusting oral medication fail, patients may be candidates for one of three device-aided therapies: deep brain stimulation (DBS), continuous subcutaneous apomorphine infusion, or continuous duodenal/jejunal levodopa/carbidopa pump infusion (DLI). These therapies differ in their invasiveness, side-effect profile, and the need for nursing care. So far, very few comparative studies have evaluated the efficacy of the three device-aided therapies for specific motor problems in advanced PD. As a result, neurologists currently lack guidance as to which therapy could be most appropriate for a particular PD patient. A group of experts knowledgeable in all three therapies reviewed the currently available literature for each treatment and identified variables of clinical relevance for choosing o

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Neurology

ISSN

0340-5354

e-ISSN

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Volume of the periodical

260

Issue of the periodical within the volume

11

Country of publishing house

DE - GERMANY

Number of pages

14

Pages from-to

2701-2714

UT code for WoS article

000326400800001

EID of the result in the Scopus database

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