Pharmacogenetics of Chronic Pain and Its Treatment

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10195055" target="_blank" >RIV/00216208:11110/13:10195055 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1155/2013/864319" target="_blank" >http://dx.doi.org/10.1155/2013/864319</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2013/864319" target="_blank" >10.1155/2013/864319</a>

Result language
angličtina
Original language name
Pharmacogenetics of Chronic Pain and Its Treatment
Original language description
This paper reviews the impact of genetic variability of drug metabolizing enzymes, transporters, receptors, and pathways involved in chronic pain perception on the efficacy and safety of analgesics and other drugs used for chronic pain treatment. Severalcandidate genes have been identified in the literature, while there is usually only limited clinical evidence substantiating for the penetration of the testing for these candidate biomarkers into the clinical practice. Further, the pain-perception regulation and modulation are still not fully understood, and thus more complex knowledge of genetic and epigenetic background for analgesia will be needed prior to the clinical use of the candidate genetic biomarkers.
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EC - Immunology
OECD FORD branch
—

Project
<a href="/en/project/NT11324" target="_blank" >NT11324: PHARMACOGENETICS OF REMIFENTANIL IN PATIENTS WITH HYPERTENSION / PREECLAMPSIA UNDERGOING CAESAREAN DELIVERY UNDER GENERAL ANAESTHESIA</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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