Fractional Carbon Dioxide Laser Improves Nodular Basal Cell Carcinoma Treatment with Photodynamic Therapy with Methyl 5-Aminolevulinate

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10196597" target="_blank" >RIV/00216208:11110/13:10196597 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11120/13:43907509

Result on the web

<a href="http://dx.doi.org/10.1111/dsu.12242" target="_blank" >http://dx.doi.org/10.1111/dsu.12242</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/dsu.12242" target="_blank" >10.1111/dsu.12242</a>

Result language

angličtina

Original language name

Fractional Carbon Dioxide Laser Improves Nodular Basal Cell Carcinoma Treatment with Photodynamic Therapy with Methyl 5-Aminolevulinate

Original language description

BACKGROUND The major limitation of photodynamic therapy with 5-aminolevulinic acid (ALA-PDT) is proper photosensitizer penetration. The nodular form of BCC (nBCC) is perceived as a contraindication to ALA-PDT because the tumor layer is thicker than 2 mm.We have improved on the results of previous studies that used an ablative laser to limit tumor thickness. A fractional laser produces skin microtubules that can improve the penetration of ALA into tumors. OBJECTIVE To evaluate the use of a fractional laser as pretreatment before ALA-PDT for nBCC treatment in an 18-month single-blind clinical trial. METHODS Fifty-six verified nBCCs were ablated using a diode laser under ultrasound control. Half of the tumors were treated 3 weeks later using a fractionalcarbon dioxide laser, and the other half were treated using curettage (control). We then immediately treated with ALA-PDT. Fluorescence and photography were evaluated and compared each month, and a final histopathologic examination was p

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Dermatologic Surgery

ISSN

1076-0512

e-ISSN

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Volume of the periodical

39

Issue of the periodical within the volume

8

Country of publishing house

US - UNITED STATES

Number of pages

7

Pages from-to

1202-1208

UT code for WoS article

000322004200010

EID of the result in the Scopus database

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