Effects of BG-12 (dimethyl fumarate) on health-related quality of life in patients with relapsing-remitting multiple sclerosis: findings from the CONFIRM study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10218645" target="_blank" >RIV/00216208:11110/14:10218645 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/14:10218645
Result on the web
<a href="http://dx.doi.org/10.1177/1352458513507818" target="_blank" >http://dx.doi.org/10.1177/1352458513507818</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1177/1352458513507818" target="_blank" >10.1177/1352458513507818</a>
Alternative languages
Result language
angličtina
Original language name
Effects of BG-12 (dimethyl fumarate) on health-related quality of life in patients with relapsing-remitting multiple sclerosis: findings from the CONFIRM study
Original language description
Multiple sclerosis (MS) has a significant impact on health-related quality of life (HRQoL) with symptoms adversely affecting many aspects of everyday living. BG-12 (dimethyl fumarate) demonstrated significant efficacy in the phase III studies DEFINE andCONFIRM in patients with relapsing-remitting MS. In CONFIRM, HRQoL was worse in patients with greater disability at baseline, and who relapsed during the study, and improved with BG-12 treatment. Mean Short Form-36 Physical Component Summary scores for BG-12 increased over 2 years and scores for placebo decreased. Coupled with clinical and neuroradiological benefits, these HRQoL results further support BG-12 as an effective oral treatment for relapsing MS.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Multiple Sclerosis
ISSN
1352-4585
e-ISSN
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Volume of the periodical
20
Issue of the periodical within the volume
2
Country of publishing house
GB - UNITED KINGDOM
Number of pages
5
Pages from-to
253-257
UT code for WoS article
000331226600019
EID of the result in the Scopus database
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