CA125 and HE4 levels in a Czech Female Population Diagnosed with Endometrial Cancer in Preoperative Management

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10227295" target="_blank" >RIV/00216208:11110/14:10227295 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11140/14:10227295 RIV/00669806:_____/14:10227295

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

CA125 and HE4 levels in a Czech Female Population Diagnosed with Endometrial Cancer in Preoperative Management

Original language description

Aim: The aim of the present study was to compare the use of cancer antigen 125 (CA125) and human epididymis protein 4 (HE4) biomarkers in patients with endometrial cancer for preoperative management and to particularly focus on relationship between CA125and HE4 and disease stage in predicting myometrial invasion or intrauterine tumor spread. Patients and Methods: Thirty-four patients diagnosed with endometrial cancer and 32 healthy controls were enrolled into the pilot study in the period between May 2012 and March 2013. Blood from all the females was collected and examined for CA125 and HE4. Based on standardized ultrasound examination, including gynecological examination, the clinical disease stage was determined. Results: We found a significant difference (p<0.0001) for means of serum levels of HE4: females with endometrial cancer, 75.5 pmol/l, versus healthy females, 40.0 pmol/l. A non-significant statistical difference was found for mean serum CA125 levels (p=0.4442): females wit

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

<a href="/en/project/EE2.3.20.0040" target="_blank" >EE2.3.20.0040: Molecular genetics of tumor and cardiovascular diseases</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Anticancer Research

ISSN

0250-7005

e-ISSN

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Volume of the periodical

34

Issue of the periodical within the volume

1A

Country of publishing house

GR - GREECE

Number of pages

5

Pages from-to

327-331

UT code for WoS article

000329765300044

EID of the result in the Scopus database

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