Differential Acute Postprandial Effects of Processed Meat and Isocaloric Vegan Meals on the Gastrointestinal Hormone Response in Subjects Suffering from Type 2 Diabetes and Healthy Controls: A Randomized Crossover Study

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10272520" target="_blank" >RIV/00216208:11110/14:10272520 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11140/14:10272520 RIV/00023761:_____/14:#0000445 RIV/00669806:_____/14:10272520 RIV/00023001:_____/14:00059028
Result on the web
<a href="http://dx.doi.org/10.1371/journal.pone.0107561" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0107561</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pone.0107561" target="_blank" >10.1371/journal.pone.0107561</a>

Result language
angličtina
Original language name
Differential Acute Postprandial Effects of Processed Meat and Isocaloric Vegan Meals on the Gastrointestinal Hormone Response in Subjects Suffering from Type 2 Diabetes and Healthy Controls: A Randomized Crossover Study
Original language description
Background: The intake of meat, particularly processed meat, is a dietary risk factor for diabetes. Meat intake impairs insulin sensitivity and leads to increased oxidative stress. However, its effect on postprandial gastrointestinal hormone (GIH) secretion is unclear. We aimed to investigate the acute effects of two standardized isocaloric meals: a processed hamburger meat meal rich in protein and saturated fat (M-meal) and a vegan meal rich in carbohydrates (V-meal). We hypothesized that the meat mealwould lead to abnormal postprandial increases in plasma lipids and oxidative stress markers and impaired GIH responses. Methods: In a randomized crossover study, 50 patients suffering from type 2 diabetes (T2D) and 50 healthy subjects underwent two 3-hmeal tolerance tests. For statistical analyses, repeated-measures ANOVA was performed. Results: The M-meal resulted in a higher postprandial increase in lipids in both groups (p<0.001) and persistent postprandial hyperinsulinemia in patie
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Project
<a href="/en/project/NT11238" target="_blank" >NT11238: Diet Intervention in Subjects with Type 2 Diabetes: Effect of Meal Frequency and Composition on Glucose Metabolism and Symptoms of Metabolic Syndrome</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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