The leiomyomatous stroma in renal cell carcinomas is polyclonal and not part of the neoplastic process

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10282579" target="_blank" >RIV/00216208:11110/14:10282579 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11140/14:10282579 RIV/00216208:11150/14:10282579 RIV/00179906:_____/14:10282579

Result on the web

<a href="http://dx.doi.org/10.1007/s00428-014-1591-9" target="_blank" >http://dx.doi.org/10.1007/s00428-014-1591-9</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00428-014-1591-9" target="_blank" >10.1007/s00428-014-1591-9</a>

Result language

angličtina

Original language name

The leiomyomatous stroma in renal cell carcinomas is polyclonal and not part of the neoplastic process

Original language description

Some renal epithelial neoplasms, such as renal angiomyoadenomatous tumor, clear cell papillary renal cell carcinoma and renal cell carcinoma with smooth muscle stroma, contain a variably prominent smooth muscle stromal component. Whether or not this leiomyomatous stroma is part of the neoplastic proliferation has not been firmly established. We studied the clonality status of 14 renal cell carcinomas with a prominent smooth muscle stromal component (four renal angiomyoadenomatous tumors/clear cell papillary carcinomas, five clear cell carcinomas, two papillary carcinomas, and three renal cell carcinomas with smooth muscle rich stroma) using the human androgen receptor assay (HUMARA). We found the leiomyomatous stromal component in all analyzable (8/14)cases to be polyclonal and therefore reactive rather than neoplastic. Based on morphological observations, we propose that the non-neoplastic leiomyomatous stromal component is likely derived from smooth muscle cells of large caliber vei

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Virchows Archiv : an international journal of pathology

ISSN

0945-6317

e-ISSN

—

Volume of the periodical

465

Issue of the periodical within the volume

1

Country of publishing house

DE - GERMANY

Number of pages

8

Pages from-to

89-96

UT code for WoS article

000338728000010

EID of the result in the Scopus database

—