Fatty acid composition indicates two types of metabolic syndrome independent of clinical and laboratory parameters

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10283736" target="_blank" >RIV/00216208:11110/14:10283736 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/14:10283736

Result on the web

<a href="http://www.biomed.cas.cz/physiolres/pdf/63/63_S375.pdf" target="_blank" >http://www.biomed.cas.cz/physiolres/pdf/63/63_S375.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Fatty acid composition indicates two types of metabolic syndrome independent of clinical and laboratory parameters

Original language description

Dietary composition and metabolism of fatty acids (FA) influence insulin resistance, atherogenic dyslipidemia and other components of the metabolic syndrome (MS). It is known that patients with MS exhibit a heterogeneous phenotype; however, the relationships of individual FA to MS components have not yet been consistently studied. We examined the plasma phosphatidylcholine FA composition of 166 individuals (68F/98M) with MS and of 188 (87F/101M) controls. Cluster analysis of FA divided the groups into two clusters. In cluster 1, there were 65.7 % of MS patients and 37.8 % of controls, cluster 2 contained 34.3 % of patients and 62.2 % of controls (P<0.001). Those with MS within cluster 1 (MS1) differed from individuals with MS in cluster 2 (MS2) by concentrations of glucose (P<0.05), NEFA (P<0.001), HOMA-IR (P<0.05), and levels of conjugated dienes in LDL (P<0.05). The FA composition in MS1 group differed from MS2 by higher contents of palmitoleic (+30 %), ?-linolenic (+22 %), dihomo-?-

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

<a href="/en/project/NT13199" target="_blank" >NT13199: Selected genetic and nutritional factors in pathogenesis of metabolic syndrome: importance of polyunsaturated fatty acids.</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Physiological Research

ISSN

0862-8408

e-ISSN

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Volume of the periodical

63

Issue of the periodical within the volume

Suppl. 3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

11

Pages from-to

"S375"-"S385"

UT code for WoS article

000345591100008

EID of the result in the Scopus database

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