Serum Adiponectin Relates to Shortened Overall Survival in Men with Squamous Cell Esophageal Cancer Treated with Preoperative Concurrent Chemoradiotherapy: A Pilot Study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10284535" target="_blank" >RIV/00216208:11110/14:10284535 - isvavai.cz</a>
Alternative codes found
RIV/00064203:_____/14:10284535 RIV/00064165:_____/14:10284535
Result on the web
<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247235/pdf/medscimonit-20-2351.pdf" target="_blank" >http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247235/pdf/medscimonit-20-2351.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.12659/MSM.891088" target="_blank" >10.12659/MSM.891088</a>
Alternative languages
Result language
angličtina
Original language name
Serum Adiponectin Relates to Shortened Overall Survival in Men with Squamous Cell Esophageal Cancer Treated with Preoperative Concurrent Chemoradiotherapy: A Pilot Study
Original language description
The convergence of nutritional, genetic, and inflammatory factors plays a significant role in the pathophysiology of squamous cell esophageal cancer (SCEC). The parameters of inflammation, indices of nutritional status, and adipocyte-derived hormones such as leptin, adiponectin, and resistin have been shown to be prognostic factors in some gastrointestinal and pancreatic cancers. Forty-two patients with SCEC were subjected to a multimodal regimen of concurrent neoadjuvant chemoradiotherapy (CRT) followed by surgery. We retrospectively analyzed the impact of pretreatment values of serum leptin, adiponectin, resistin, soluble leptin receptor, C-reactive protein, TNF alpha, leukocytes, and indices of nutritional status (BMI, plasma total protein, albumin,cholesterol, and triacylglycerols) on overall survival (OS). Univariate analysis revealed significant a negative correlation between OS and serum adiponectin (p=0.027), and a positive relationship was found between serum albumin (p=0.002
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
—
Result continuities
Project
<a href="/en/project/NT12331" target="_blank" >NT12331: Early assessment of effectivness of neoadjuvant chemotherapy for carcinoma of the esophagus and esophago-gastric junction using FDG-PET/CT.</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Medical Science Monitor [online]
ISSN
1643-3750
e-ISSN
—
Volume of the periodical
20
Issue of the periodical within the volume
november
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
2351-2357
UT code for WoS article
000350045200001
EID of the result in the Scopus database
—