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Serum Adiponectin Relates to Shortened Overall Survival in Men with Squamous Cell Esophageal Cancer Treated with Preoperative Concurrent Chemoradiotherapy: A Pilot Study

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10284535" target="_blank" >RIV/00216208:11110/14:10284535 - isvavai.cz</a>

  • Alternative codes found

    RIV/00064203:_____/14:10284535 RIV/00064165:_____/14:10284535

  • Result on the web

    <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247235/pdf/medscimonit-20-2351.pdf" target="_blank" >http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247235/pdf/medscimonit-20-2351.pdf</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.12659/MSM.891088" target="_blank" >10.12659/MSM.891088</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Serum Adiponectin Relates to Shortened Overall Survival in Men with Squamous Cell Esophageal Cancer Treated with Preoperative Concurrent Chemoradiotherapy: A Pilot Study

  • Original language description

    The convergence of nutritional, genetic, and inflammatory factors plays a significant role in the pathophysiology of squamous cell esophageal cancer (SCEC). The parameters of inflammation, indices of nutritional status, and adipocyte-derived hormones such as leptin, adiponectin, and resistin have been shown to be prognostic factors in some gastrointestinal and pancreatic cancers. Forty-two patients with SCEC were subjected to a multimodal regimen of concurrent neoadjuvant chemoradiotherapy (CRT) followed by surgery. We retrospectively analyzed the impact of pretreatment values of serum leptin, adiponectin, resistin, soluble leptin receptor, C-reactive protein, TNF alpha, leukocytes, and indices of nutritional status (BMI, plasma total protein, albumin,cholesterol, and triacylglycerols) on overall survival (OS). Univariate analysis revealed significant a negative correlation between OS and serum adiponectin (p=0.027), and a positive relationship was found between serum albumin (p=0.002

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NT12331" target="_blank" >NT12331: Early assessment of effectivness of neoadjuvant chemotherapy for carcinoma of the esophagus and esophago-gastric junction using FDG-PET/CT.</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Medical Science Monitor [online]

  • ISSN

    1643-3750

  • e-ISSN

  • Volume of the periodical

    20

  • Issue of the periodical within the volume

    november

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    7

  • Pages from-to

    2351-2357

  • UT code for WoS article

    000350045200001

  • EID of the result in the Scopus database