Strategies to diagnose ovarian cancer: new evidence from phase 3 of the multicentre international IOTA study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10284689" target="_blank" >RIV/00216208:11110/14:10284689 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/14:10284689

Result on the web

<a href="http://dx.doi.org/10.1038/bjc.2014.333" target="_blank" >http://dx.doi.org/10.1038/bjc.2014.333</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/bjc.2014.333" target="_blank" >10.1038/bjc.2014.333</a>

Result language

angličtina

Original language name

Strategies to diagnose ovarian cancer: new evidence from phase 3 of the multicentre international IOTA study

Original language description

Background: To compare different ultrasound-based international ovarian tumour analysis (IOTA) strategies and risk of malignancy index (RMI) for ovarian cancer diagnosis using a meta-analysis approach of centre-specific data from IOTA3. Methods: This prospective multicentre diagnostic accuracy study included 2403 patients with 1423 benign and 980 malignant adnexal masses from 2009 until 2012. All patients underwent standardised transvaginal ultrasonography. Test performance of RMI, subjective assessment(SA) of ultrasound findings, two IOTA risk models (LR1 and LR2), and strategies involving combinations of IOTA simple rules (SRs), simple descriptors (SDs) and LR2 with and without SA was estimated using a meta-analysis approach. Reference standard washistology after surgery. Results: The areas under the receiver operator characteristic curves of LR1, LR2, SA and RMI were 0.930 (0.917-0.942), 0.918 (0.905-0.930), 0.914 (0.886-0.936) and 0.875 (0.853-0.894). Diagnostic one-step and two-

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FK - Gynaecology and obstetrics

OECD FORD branch

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Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

British Journal of Cancer

ISSN

0007-0920

e-ISSN

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Volume of the periodical

111

Issue of the periodical within the volume

4

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

680-688

UT code for WoS article

000341024100008

EID of the result in the Scopus database

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