Estimation of the potential overall impact of human papillomavirus vaccination on cervical cancer cases and deaths

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10284796" target="_blank" >RIV/00216208:11110/14:10284796 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/14:10284796

Result on the web

<a href="http://dx.doi.org/10.1016/j.vaccine.2013.11.049" target="_blank" >http://dx.doi.org/10.1016/j.vaccine.2013.11.049</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.vaccine.2013.11.049" target="_blank" >10.1016/j.vaccine.2013.11.049</a>

Result language

angličtina

Original language name

Estimation of the potential overall impact of human papillomavirus vaccination on cervical cancer cases and deaths

Original language description

Background: Human papillomavirus (HPV) vaccination offers potential for primary prevention of HPV-related pre-cancers and cancers as demonstrated in clinical trials. Mathematical models have estimated the potential real-life impact of vaccination on theburden of cervical cancer (CC). However, these are restricted to evaluations in a limited number of countries. Methods: Potential decline in CC cases and deaths with the AS04-adjuvanted HPV-16/18 vaccine of young girls naive to HPV, was estimated at steady-state (vaccine coverage: 0-100%) based on clinical trial and country-specific incidence data. Data on vaccine efficacy were taken from the end of study PATRICIA trial of the AS04-adjuvanted HPV-16/18 vaccine. The numbers of cases and deaths due to HPV-16/18 were estimated and compared with those due to any HPV type to estimate the additional cases prevented. This difference estimates CC cases and deaths avoided due to protection against non-vaccine HPV types. Cost-offsets due to reduc

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FK - Gynaecology and obstetrics

OECD FORD branch

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Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Vaccine

ISSN

0264-410X

e-ISSN

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Volume of the periodical

32

Issue of the periodical within the volume

6

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

733-739

UT code for WoS article

000331501900015

EID of the result in the Scopus database

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