Distinct chromatin organization in the germ line founder cell of the Caenorhabditis elegans embryo

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10285509" target="_blank" >RIV/00216208:11110/14:10285509 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1111/dgd.12160" target="_blank" >http://dx.doi.org/10.1111/dgd.12160</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/dgd.12160" target="_blank" >10.1111/dgd.12160</a>

Result language

angličtina

Original language name

Distinct chromatin organization in the germ line founder cell of the Caenorhabditis elegans embryo

Original language description

Cells belonging to the germ lineage segregate physically and molecularly from their somatic neighbors during embryogenesis. While germ line-specific chromatin modifications have been identified at later stages in the Caenorhabditis elegans nematode, nonehave been found in the single P-4 germ line founder cell that arises at the beginning of gastrulation. Using light and electron microscopy, we now report that the chromatin organization in the germ line founder cell of the early C.elegans embryo is distinct from that in the neighboring somatic cells. This unique organization is characterized by a greater chromatin compaction and an expansion of the interchromatin compartment. The ultrastructure of individual chromatin domains does not differ between germ line and somatic cells, pointing to a specific organization mainly at the level of the whole nucleus. We show that this higher order reorganization of chromatin is not a consequence of the P-4 nucleus being smaller than somatic nuclei

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Development Growth and Differentiation

ISSN

0012-1592

e-ISSN

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Volume of the periodical

56

Issue of the periodical within the volume

9

Country of publishing house

JP - JAPAN

Number of pages

10

Pages from-to

605-614

UT code for WoS article

000346479200002

EID of the result in the Scopus database

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