Tolerability of the capsaicin 8% patch following pretreatment with lidocaine or tramadol in patients with peripheral neuropathic pain: A multicentre, randomized, assessor-blinded study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10286825" target="_blank" >RIV/00216208:11110/14:10286825 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/14:10286825

Result on the web

<a href="http://dx.doi.org/10.1002/j.1532-2149.2014.00479.x" target="_blank" >http://dx.doi.org/10.1002/j.1532-2149.2014.00479.x</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/j.1532-2149.2014.00479.x" target="_blank" >10.1002/j.1532-2149.2014.00479.x</a>

Result language

angličtina

Original language name

Tolerability of the capsaicin 8% patch following pretreatment with lidocaine or tramadol in patients with peripheral neuropathic pain: A multicentre, randomized, assessor-blinded study

Original language description

BackgroundApplication of the capsaicin 8% patch is associated with treatment-related discomfort. Consequently, pretreatment for 60min with anaesthetic cream is recommended; however, this may be uncomfortable and time consuming. MethodsWe conducted a multicentre, randomized (1:1), assessor-blinded study in patients with peripheral neuropathic pain to assess tolerability of the capsaicin patch following topical lidocaine (4%) or oral tramadol (50mg) pretreatment. The primary endpoint was the proportion ofpatients tolerating capsaicin patch application (ability to receive 90% of a 60-min application). Numeric Pain Rating Scale (NPRS) scores were assessed before, during and after treatment. ResultsOverall, 122 patients were included (61 per arm). The capsaicin patch was tolerated by 121 patients. Tolerability of the capsaicin patch was similar following pretreatment with lidocaine and tramadol. Following patch application, pain levels increased up to 55min (change from baseline of 1.3 for

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Journal of Pain

ISSN

1090-3801

e-ISSN

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Volume of the periodical

18

Issue of the periodical within the volume

9

Country of publishing house

GB - UNITED KINGDOM

Number of pages

8

Pages from-to

1240-1247

UT code for WoS article

000341979800005

EID of the result in the Scopus database

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