Heterochromatin variants in human karyotypes: a possible association with reproductive failure

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10287009" target="_blank" >RIV/00216208:11110/14:10287009 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/14:10287009

Result on the web

<a href="http://dx.doi.org/10.1016/j.rbmo.2014.04.021" target="_blank" >http://dx.doi.org/10.1016/j.rbmo.2014.04.021</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.rbmo.2014.04.021" target="_blank" >10.1016/j.rbmo.2014.04.021</a>

Result language

angličtina

Original language name

Heterochromatin variants in human karyotypes: a possible association with reproductive failure

Original language description

Heterochromatin variants are commonly found during cytogenetic examinations, and chromosomes 1, 9, 16 and Y are commonly involved in these variations. These variants are believed to be clinically insignificant variations in human karyotypes. Nevertheless, reproductive failure has been frequently discussed as possibly being associated with these variants. Various authors have reported a significantly elevated incidence of these variants in individuals with idiopathic reproductive failure compared with individuals with no such history. This study compared the incidence of heterochromatin variants in individuals with idiopathic reproductive failure (n = 1036) with that of a control group of healthy fetuses (n = 995) indicated for prenatal karyotype examination solely based on the advanced ages of their mothers. The heterochromatin variants occurred more frequently in the reproductive failure group than in the controls (P = 0.006). Regarding individual chromosomes, chromosome 9 variants we

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FK - Gynaecology and obstetrics

OECD FORD branch

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Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Reproductive BioMedicine Online

ISSN

1472-6483

e-ISSN

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Volume of the periodical

29

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

245-250

UT code for WoS article

000341378100014

EID of the result in the Scopus database

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