Collaborative EDNAP exercise on the IrisPlex system for DNA-based prediction of human eye colour

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10292114" target="_blank" >RIV/00216208:11110/14:10292114 - isvavai.cz</a>

Alternative codes found

RIV/00007064:K01__/14:N0000003

Result on the web

<a href="http://dx.doi.org/10.1016/j.fsigen.2014.04.006" target="_blank" >http://dx.doi.org/10.1016/j.fsigen.2014.04.006</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.fsigen.2014.04.006" target="_blank" >10.1016/j.fsigen.2014.04.006</a>

Result language

angličtina

Original language name

Collaborative EDNAP exercise on the IrisPlex system for DNA-based prediction of human eye colour

Original language description

The IrisPlex system is a DNA-based test system for the prediction of human eye colour from biological samples and consists of a single forensically validated multiplex genotyping assay together with a statistical prediction model that is based on genotypes and phenotypes from thousands of individuals. IrisPlex predicts blue and brown human eye colour with, on average, >94% precision accuracy using six of the currently most eye colour informative single nucleotide polymorphisms (HERC2 rs12913832, OCA2 rs1800407, SLC24A4 rs12896399, SLC45A2 (MATP) rs16891982, TYR rs1393350, and IRF4 rs12203592) according to a previous study, while the accuracy in predicting non-blue and non-brown eye colours is considerably lower. In an effort to vigorously assess the IrisPlex system at the international level, testing was performed by 21 laboratories in the context of a collaborative exercise divided into three tasks and organised by the European DNA Profiling (EDNAP) Group of the International Society

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

<a href="/en/project/VG20122015071" target="_blank" >VG20122015071: Development, Application and Automation of Genetic Analysis Technologies and Procedures Aimed at Predicting and Identifying Perpetrators and Victims of Terrorist Attacks, Crimes nad Natural Disasters.</a><br>

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Forensic Science International: Genetics

ISSN

1872-4973

e-ISSN

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Volume of the periodical

11

Issue of the periodical within the volume

July

Country of publishing house

IE - IRELAND

Number of pages

11

Pages from-to

241-251

UT code for WoS article

000336669300036

EID of the result in the Scopus database

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